Breast Implant-Associated Anaplastic Large Cell Lymphoma (ALCL): A Case Report.

Autor: Evren, Sevan, Khoury, Thaer, Neppalli, Vishalla, Cappuccino, Helen, Hernandez-Ilizaliturri, Francisco J., Kumar, Prasanna
Předmět:
Zdroj: American Journal of Case Reports; 2017, Vol. 18, p605-610, 6p
Abstrakt: Objective: Rare disease Background: Anaplastic large cell lymphomas (ALCL) are a rare type of primary breast lymphoma. The association between breast implants and ALCL was first described in 1997 and since then 34-173 cases have been presented. The annual incidence of breast implant-associated ALCL (BI-ALCL) is 0.1-0.3 per 100 000 women who undergo breast reconstruction, and cases are often underreported due to the rarity of these tumors. BI-ALCL arises from the inflammatory T cells surrounding the fibrous capsule, and most tumors are in situ. Case Report: Here, we present the case of a 51-year-old woman with ALCL following bilateral silicone breast implants. The patient presented with breast enlargement and tenderness 9 years following reconstructive surgery. Imagining studies showed fluid collection surrounding the affected breast implant. Staging studies and histocytopathology examination confirmed the presence BI-ALCL without capsular invasion or metastasis. Complete surgical excision was performed. The patient continues to be in complete remission. Conclusions: Due to the rarity of these tumors, establishing the diagnosis of BI-ALCL can be challenging and requires a multidisciplinary approach. Clinicians should be aware of the relationship between breast implants and BI-ALCL. [ABSTRACT FROM AUTHOR]
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