Elevated resistive index in the hepatic artery as a predictor of fulminant hepatic failure in patients with acute viral hepatitis: a prospective study using Doppler ultrasound.

Autor:	Tanaka, Katsuaki, Numata, Kazushi, Morimoto, Manabu, Shirato, Kazuhito, Saito, Satoru, Imada, Toshio, Arata, Shinju, Sugiyama, Mitsugi
Předmět:	HEPATIC artery VIRAL hepatitis LIVER failure LONGITUDINAL method VASCULAR resistance COLOR Doppler ultrasonography PREDICTIVE tests ACUTE diseases DISEASE complications
Zdroj:	Digestive Diseases & Sciences; May2004, Vol. 49 Issue 5, p833-842, 10p
Abstrakt:	To assess the sensitivity and specificity of the resistive index of the hepatic artery, which is related to the vascular resistance of the artery, for the prediction of fulminant hepatic failure, we performed Doppler ultrasonography examinations on the hepatic arteries of 72 patients with acute viral hepatitis (25 of whom developed fulminant hepatic failure and 47 of whom recovered without developing fulminant hepatic failure) as well as the hepatic arteries of age- and sex-matched controls. The mean resistive index of the hepatic arteries in patients who developed fulminant hepatic failure was significantly larger than that of patients who recovered without developing fulminant hepatic failure (P < 0.01). When a resistive index cutoff level of 0.74 was used, an 84% sensitivity and a 94% specificity were obtained for the prediction of fulminant hepatic failure. An elevated resistive index of the hepatic artery may be useful for predicting the patient's clinical outcome and determining the need for a liver transplantation in patients with acute viral hepatitis. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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