| Autor: |
Milagres, Luana Cupertino, Rocha, Naruna Pereira, Filgueiras, Mariana de Santis, Albuquerque, Fernanda Martins de, Castro, Ana Paula Pereira, Pessoa, Milene Cristine, Gouveia Peluzio, Maria do Carmo, Novaes, Juliana Farias de |
| Předmět: |
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| Zdroj: |
Public Health Nutrition; Nov2017, Vol. 20 Issue 16, p2878-2886, 9p |
| Abstrakt: |
Objective: To assess the prevalence of vitamin D insufficiency and deficiency and its association with cardiometabolic risk factors, controlled by adiposity, in a representative sample of prepubescent children.Design: Cross-sectional population-based study. Body composition was evaluated by dual-energy X-ray absorptiometry. Anthropometric measures and blood pressure were performed. Laboratory analyses were performed to determine the levels of vitamin D (25-hydroxyitamin D; 25(OH)D), glucose, insulin, serum lipids and intact parathyroid hormone. Dietary intake was assessed by three 24 h recalls.Setting: Viçosa, Minas Gerais, Brazil, 2015.Subjects: Representative sample of 378 children aged 8 and 9 years from urban schools.Results: Inadequate serum concentrations of 25(OH)D were diagnosed in more than half of the children and none of them met the recommended vitamin D intake. After adjusting for confounding factors in the multiple regression analysis, lower prevalence of insulin resistance and hypertriacylglycerolaemia was found in children with serum 25(OH)D levels ≥75 nmol/l (prevalence ratio=0·25; 95 % CI 0·08, 0·85) and ≥50 nmol/l (prevalence ratio=0·61; 95 % CI 0·37, 0·99), respectively. However, after adjusting for different indicators of adiposity, insulin resistance remained independently associated and the association with hypertriacylglycerolaemia was lost after adjusting for central adiposity. The prevalence of vitamin D insufficiency/deficiency was associated with the number of cardiometabolic alterations in children.Conclusions: The study results showed that prevalence of vitamin D insufficiency/deficiency was high among the children and insulin resistance was the main cardiometabolic alteration associated with this condition, even in a tropical climate country such as Brazil. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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