| Autor: |
Kassiri, Hossein, Tonekaboni, Sana, Salam, M. Tariqus, Soltani, Nima, Abdelhalim, Karim, Velazquez, Jose Luis Perez, Genov, Roman |
| Zdroj: |
IEEE Transactions on Biomedical Circuits & Systems; Oct2017, Vol. 11 Issue 5, p1026-1040, 15p |
| Abstrakt: |
First, existing commercially available open-loop and closed-loop implantable neurostimulators are reviewed and compared in terms of their targeted application, physical size, system-level features, and performance as a medical device. Next, signal processing algorithms as the primary strength point of the closed-loop neurostimulators are reviewed, and various design and implementation requirements and trade-offs are discussed in details along with quantitative examples. The review results in a set of guidelines for algorithm selection and evaluation. Second, the implementation of an inductively-powered seizure-predicting microsystem for monitoring and treatment of intractable epilepsy is presented. The miniaturized system is comprised of two miniboards and a power receiver coil. The first board hosts a 24-channel neurostimulator system on chip [15] fabricated in a 0.13\;\mu \textm CMOS technology and performs neural recording, on-chip digital signal processing, and electrical stimulation. The second board communicates recorded brain signals as well as signal processing results wirelessly. The multilayer flexible coil receives inductively-transmitted power. The system is sized at 2 $\times$ 2 \times$ 0.7 \text{cm}^3 and weighs 6 g. The approach is validated in the control of chronic seizures in vivo in freely moving rats. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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