Should Serum Protein Electrophoresis Be a Surrogate for Liver Biopsy in Some Cases of Alpha1 Antitrypsin Deficiency?

Autor: Hokama, Newton Key, Moraes, Marcelo Padovani de Toledo, Hokama, Paula de Oliveira Montandon, Romeiro, Fernando Gomes
Předmět:
Zdroj: Case Reports in Hepatology; 9/28/2017, p1-3, 3p
Abstrakt: Most patients with alpha1 antitrypsin deficiency do not receive this diagnosis until developing severe complications, in particular when respiratory symptoms are absent. This is a reason for making alpha1 antitrypsin deficiency a possible diagnosis among patients with cryptogenic cirrhosis or other conditions of liver disease without a clear etiology. In this report, a case of cryptogenic cirrhosis is presented, showing the role of serum protein electrophoresis in the diagnosis, which was made before liver biopsy. Therefore, the possibility of using a typical pattern of serum protein electrophoresis as a surrogate for liver biopsy in alpha1 antitrypsin deficiency is discussed. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index