A glucagon-like peptide-1 receptor agonist reduces intracranial pressure in a rat model of hydrocephalus.

Autor: Botfield, Hannah F., Uldall, Maria S., Westgate, Connar S. J., Mitchell, James L., Hagen, Snorre M., Gonzalez, Ana Maria, Hodson, David J., Jensen, Rigmor H., Sinclair, Alexandra J.
Předmět:
Zdroj: Science Translational Medicine; 8/23/2017, Vol. 9 Issue 404, p1-11, 11p
Abstrakt: The article focuses on a research conducted for analyzing use of glucagon-like peptide-1 receptors (GLP-1R) for minimizing the intracranial pressure (ICP) in idiopathic intracranial hypertension or hydrocephalus. Various topics discussed include research on female rats, modulation of cerebrospinal fluid (CSF) secretion and GLP-1R expression.
Databáze: Complementary Index