| Abstrakt: |
Introduction: Propolis is one of the few natural remedies that have maintained its popularity over a long period of time. It's a natural antibiotic is a resinous substance that honey bees collect from tree buds, sap flow, shrubs and other botanic sources. Propolis is a subject of recent research in dentistry, since there is some evidence that propolis may actively protect against oral disease due to its antimicrobial, anti-inflammatory and host modulatory properties. The present research was undertaken to test the efficacy of propolis as an adjunct to SRP on clinical Parameters and cytokine levels in patients with chronic periodontitis. Methodology: 15 patients diagnosed with chronic generalized periodontitis were included in the study. Two quadrants with maximum number of sites with PPD measuring ≥ 6mm were selected from each patient. The clinical parameters like MGI, BOP, PPD, CAL were recorded for the selected quadrants in all teeth excluding third molars. 3µlitre of GCF were collected from a site with deepest probing pocket in each quadrant. Then the patients were subjected for full mouth SRP. Then each quadrant is randomly assigned for group-I and group-II. In test group, the quadrant will be subjected for Irrigation with 3mL of 30% Propolis solution per tooth on 0, 7, 15 & 21st day. In placebo group, the quadrant will be subjected for Irrigation with 3mL of distilled water per tooth on 0, 7th, 15th and 21st day. In both the groups clinical parameters and GCF collection was repeated after two months and three months. Results: Three months following nonsurgical therapy and sub-gingival irrigation of 30% propolis four times (once in every week), there was significant improvement in clinical parameters and immunological parameters i.e. IL-1β, IL-4. Conclusion: Sub gingival irrigation of 30% propolis as an adjunct to SRP is beneficial in reducing the periodontal inflammation and arresting the periodontal tissue destruction when followed up for 3 months. [ABSTRACT FROM AUTHOR] |
