| Autor: |
Tianjia Liu, Jan, Gibbons, R. J., Hay, D. I. |
| Předmět: |
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| Zdroj: |
Oral Microbiology & Immunology; Jun1990, Vol. 5 Issue 3, p143-148, 6p |
| Abstrakt: |
Strains of Streptococcus cricetus and Streptococcus rattus exhibited striking differences in their ability to bind to different types of collagen. For example, S. cricetus AHT bound in highest numbers to hydroxyapatite (HA) treated with human type V collagen, while rat type I collagen was ineffective. In contrast, human type V collagen was least effective in promoting of S. rattus LB-1, while treatment with rat or human type I collagen was effective. Adsorption of both type I collagen-treated HA showed a high correlation with a Langmuir model. Estimation of adsorption parameters indicated there were greater numbers of binding sites with higher for S. rattus LB-1 than for S. cricetus AHT. Treatment of HA with their the alpha 1(1) or alpha 2(1) polpeptide chains of collagen was effective in promoting adhesion of S. rattus LB-1 cells. In contrast, the alpha 2(1) chain was more effective than the alpha 1(1), chain for S. crietus AHT. These observations indicate that S. cricetusAHT and S. rattus LB-1 cells bind to different segments of collagen molecules. Adhession of both species was also promoted by collagen-rich fractions of human dentin. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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