Autor: |
Jian Wang, Ru-Yan Zhang, Ya-Cong Wang, Xiang-Zhao Chen, Xu-Guang Yin, Jing-Jing Du, Ze Lei, Ling-Ming Xin, Xiao-Fei Gao, Zheng Liu, Jun Guo |
Předmět: |
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Zdroj: |
Synlett; 2017, Vol. 28 Issue 15, p1934-1938, 5p |
Abstrakt: |
Along with N-hydroxysuccinimidyl, p-nitrophenyl, and phenylseleno esters, tetra- and penta-fluorophenyl esters were comparatively evaluated in term of their reactivity and hydrolytic stability. Their homobifunctional cross-linkers were prepared to conjugate proteins with small molecules, including carbohydrates, fluorescent dyes, and poly(ethylene glycol) monomethyl ether. The conjugations proceeded under mild conditions, affording the corresponding protein conjugates with good efficiency. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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