Urinary fluoride excretion by preschool children in six European countries.

Autor: Ketley, Clare E., Cochran, Judith A., Holbrook, W. Peter, Sanches, Leonor, van Loveren, Cor, Oila, Anna-Maria, O'Mullane, Denis M.
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Zdroj: Community Dentistry & Oral Epidemiology; Apr2004 Supplement 1, Vol. 32, p62-68, 7p
Abstrakt: Ketley CE, Cochran JA, Holbrook WP, Sanches L, van Loveren C, Oila A-M, O'Mullane DM. Urianry fluoride excretion by preschool children in six European countries. Community Dent Oral Epidemiol 2004; 32 (Suppl. 1): 62-68. © Blackwell Munksgaard, 2004 Objective: To measure and compare 24-h urinary fluoride excretion in children aged 1.5-3.5 years from European study sites and to use these data to estimate the 24-h fluoride intake. Method: Twenty-four-hour urine samples were collected from 3-year-old children ( n = 86) who were already participating in a European multicentre study. Samples were collected from Cork, Ireland ( n = 19) where the water is fluoridated to a concentration between 0.8 and 1.0 ppm and from five sites with a water fluoride concentration <0.15 ppm: Knowsley, England ( n = 18); Oulu, Finland ( n = 18); Reykjavik, Iceland ( n = 4); Haarlem, the Netherlands ( n = 6); Almada/Setubal, Portugal ( n = 21). The volume of the samples was measured; they were analysed for fluoride concentration and the 24-h urinary fluoride excretion was calculated. From this an estimate of the daily fluoride intake was made. Results: It was found that the mean fluoride excretion in response to the usual conditions of fluoride intake in the children in the nonfluoridated areas ranged from 0.16 mg (±0.08) in Oulu to 0.33 mg (±0.27) in Almada/Setubal with an overall mean of 0.23 mg (±0.19). The mean 24-h fluoride excretion in fluoridated Cork was 0.37 mg (±0.11). There was a significant difference between the fluoride excretion in the nonfluoridated areas and that in the fluoridated areas, and the data were broadly in agreement with WHO standards. Conclusions: The daily urinary fluoride excretion and estimated fluoride intake in these children appeared to be within acceptable limits. [ABSTRACT FROM AUTHOR]
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