| Autor: |
Koyama, Kazuya, Mitsumoto, Takuya, Shiraishi, Takahiro, Tsuda, Keisuke, Nishiyama, Atsushi, Inoue, Kazumasa, Yoshikawa, Kyosan, Hatano, Kazuo, Kubota, Kazuo, Fukushi, Masahiro |
| Zdroj: |
Radiological Physics & Technology; Sep2017, Vol. 10 Issue 3, p311-320, 10p |
| Abstrakt: |
We aimed to determine the difference in tumor volume associated with the reconstruction model in positron-emission tomography (PET). To reduce the influence of the reconstruction model, we suggested a method to measure the tumor volume using the relative threshold method with a fixed threshold based on peak standardized uptake value (SUV). The efficacy of our method was verified using F-2-fluoro-2-deoxy- d-glucose PET/computed tomography images of 20 patients with lung cancer. The tumor volume was determined using the relative threshold method with a fixed threshold based on the SUV. The PET data were reconstructed using the ordered-subset expectation maximization (OSEM) model, the OSEM + time-of-flight (TOF) model, and the OSEM + TOF + point-spread function (PSF) model. The volume differences associated with the reconstruction algorithm (%VD) were compared. For comparison, the tumor volume was measured using the relative threshold method based on the maximum SUV (SUV). For the OSEM and TOF models, the mean %VD values were −0.06 ± 8.07 and −2.04 ± 4.23% for the fixed 40% threshold according to the SUV and the SUV respectively. The effect of our method in this case seemed to be minor. For the OSEM and PSF models, the mean %VD values were −20.41 ± 14.47 and −13.87 ± 6.59% for the fixed 40% threshold according to the SUV and SUV, respectively. Our new method enabled the measurement of tumor volume with a fixed threshold and reduced the influence of the changes in tumor volume associated with the reconstruction model. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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