| Autor: |
Brian A. Bidlingmeyer, Alan D. Broske |
| Předmět: |
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| Zdroj: |
Journal of Chromatographic Science; Feb2004, Vol. 42 Issue 2, p100-106, 7p |
| Abstrakt: |
The phenomenon of aqueous mobile phase induced retention time loss, which has also been referred to as phase-collapse behavior, is investigated using a variety of stationary phases with an aqueous mobile phase. The loss of retention of several water-soluble B vitamins is measured as a function of silica pore size, bonded-phase chemistry, and bonded stationary phase density. It is found that these variables influence the magnitude of the retention time loss behavior and that controlling/optimizing these variables can result in a stationary phase with sufficient retention of the analyte without the column exhibiting the so-called phase-collapse behavior. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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