| Autor: |
Bebbington, Magnus W. P. |
| Předmět: |
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| Zdroj: |
Chemical Society Reviews; 8/21/2017, Vol. 46 Issue 16, p5059-5109, 51p |
| Abstrakt: |
For the first time a general overview of approaches to the synthesis of natural product analogues is presented. This reflects a process of evolution of natural product synthesis which has accelerated in the years since the implementation of diversity-oriented synthesis, which has emerged in parallel with collective synthesis, diverted total synthesis and the preparation of truncated natural products optimised for biological activity. A method involving computational assessment for the validation of core-modified natural product analogues is discussed. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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