Autor: |
Gonzalez, U. A., Menendez, C., Saitua, H. A., Rigau, J. |
Předmět: |
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Zdroj: |
Separation Science & Technology; 2017, Vol. 52 Issue 12, p1992-2001, 10p |
Abstrakt: |
Bovine serum albumin produced by heat shock from bovine plasma has been researched for the effects of sodium caprylate concentration [Cap], temperature (T), and pH on yield (Yield%) and purity (BSA%). Response surface methodology and desirability function approaches were applied to optimize its process. The best compromise solution was found with BSA% = 95.0 and Yield% = 28.5 for a [Cap] = 2 mM,T= 67.9°C, and pH = 5. A Monte Carlo simulation showed that it is possible to obtain excellent values for each individual response. However, a techno-economic feasibility study must be carried out to determine which one is the best option. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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