Palladium- and/or Copper-Catalyzed Cross-Coupling Reactions of Paramagnetic Vinyl Bromides and Iodides.

Autor: Úr, Györgyi, Fekete, Gergely Gulyás, Jekő, József, Hideg, Kálmán, Kálai, Tamás
Předmět:
Zdroj: Synthesis; 2017, Vol. 49 Issue 16, p3740-3748, 9p
Abstrakt: A series of new 3-substituted-4-iodo-(2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-yl)oxidanyl compounds is synthesized to achieve NH2- and SH-specific spin labels. The new vinyl iodides are tested in Sonogashira and Buchwald-Hartwig cross-coupling reactions to produce a paramagnetic ß-amino acid ester, pyrroline nitroxidecondensed heterocycles, including a paramagnetic a,a'-dipyridyl ligand and a spin-labeled sulfonamide. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index