Sustainability of treatment effect of a 3-year early intervention programme for first-episode psychosis.

Autor: Wing Chung Chang, Kit Wa Chan, Sherry, Yu Hai Chen, Eric, Wing Yan Kwong, Vivian, Sin Kei Lau, Emily, Sau Man Wong, Corine, Lai Ming Hui, Christy, Ho Ming Lee, Edwin, Hon Cheong So, Hoi Kei Chan, Gloria, Tsz Ting Jim, Olivia, Chang, Wing Chung, Kwong, Vivian Wing Yan, Lau, Emily Sin Kei, So, Hon Cheong, Wong, Corine Sau Man, Chan, Gloria Hoi Kei, Jim, Olivia Tsz Ting, Hui, Christy Lai Ming, Chan, Sherry Kit Wa
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Zdroj: British Journal of Psychiatry; Jul2017, Vol. 211 Issue 1, p37-44, 8p
Abstrakt: BackgroundEvidence indicates that the positive effects of 2-year early intervention services for psychosis are not maintained after service withdrawal. Optimal duration of early intervention in sustaining initial improved outcomes remains to be determined.AimsTo examine the sustainability of the positive effects of an extended, 3-year, early intervention programme for patients with first-episode psychosis (FEP) after transition to standard care.MethodA total of 160 patients, who had received a 2-year early intervention programme for FEP, were enrolled to a 12-month randomised-controlled trial (ClinicalTrials.gov: NCT01202357) comparing a 1-year extension of the early intervention (3-year specialised treatment) with step-down care (2-year specialised treatment). Participants were followed up and reassessed 2 and 3 years after inclusion to the trial.ResultsThere were no significant differences between the treatment groups in outcomes on functioning, symptom severity and service use during the post-trial follow-up period.ConclusionsThe therapeutic benefits achieved by the extended, 3-year early intervention were not sustainable after termination of the specialised service. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index