Autor: |
Wu, Qinglin, Fenton, Benjamin A., Wojtaszek, Jessica L., Zhou, Pei |
Předmět: |
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Zdroj: |
Chemical Communications; 8/7/2017, Vol. 53 Issue 61, p8541-8544, 4p |
Abstrakt: |
CEST-NMR spectroscopy is a powerful tool for probing the conformational dynamics of macromolecules. We present a HNdec-CEST experiment that simplifies the relaxation matrix, reduces fitting parameters, and enhances signal resolution. Importantly, fitting of HNdec-CEST profiles enables robust extraction of exchange rates as well as excited-state chemical shifts and populations. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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