| Autor: |
Szalecki, Krzysztof, Koziara, Henryk, Rola, Rafal, Nauman, Pawel, Mandat, Tomasz |
| Zdroj: |
Stereotactic & Functional Neurosurgery; 2017 Supplement, Vol. 95, p250-250, 1/3p |
| Abstrakt: |
Background: Dystonia, with variety of its clinical forms is a multidisciplinary challenge for physicians. Author presents a group of patients with various dystonia types treated with subthalamic (STN) or pallidal (GPi) deep brain stimulation (DBS). Methods: 42 patients (20 male, 22 female) age from 6 to 64 (mean 31,4) affected by dystonia were treated with DBS. 16 patients diagnosed with idiopathic general dystonia, 14 NBIA- related general dystonia, 5 hemidystonia, 3 torcicollis, 2 DYT-1- related general dystonia, 1 myoclonic dystonia and 1 oromandibular dystonia. The patients were evaluated with the Fahn- Marsden Scale (FMS), Unified Dystonia Rating Scale (UDRS), Global Dystonia Scale (GDS) and torticollis patients were evaluated with Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) before treatment and 6, 12 and 24 moths after the procedure. The permanent electrodes were implanted to GPi in 31 cases or to STN in 9 patients or GPi and STN in 2 patients. The target was identified with direct and indirect method. Intrasurgical macrostimulation and microrecording were used for neurophysiological evaluation of the target. Results: No serious morbidity or mortality were noticed in the group. Local chest hematoma was reported at the region, where internal pulse generator was implanted. Best results were achieved among patients with with DYT-1 related general dystonia (mean 91%) and oromandibular dystonia (84%). The poorest results were noted at the PKAN group (mean 41%). Mean improvement of 72% was achieved in all groups. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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