Autor: |
Jing Lu, Caplan, Michael S., Saraf, Anita P., Li, Dan, Adler, Luba, Xuesong Liu, Jilling, Tamas |
Předmět: |
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Zdroj: |
American Journal of Physiology: Gastrointestinal & Liver Physiology; Feb2004, Vol. 286, pG340-G350, 11p, 3 Diagrams, 14 Graphs |
Abstrakt: |
Determines whether platelet-activating factor (PAF) induces apoptosis in enterocytes in rat intestinal epithelial cells and delineates the mechanism of action. Testing of the hypothesis that the level PAF-degrading enzyme PAF acetylhydrolase was lower in mucosal samples from distal ileum in Chron's disease patients than in controls; Observation that a faulty regulation of apoptosis plays a role in intestinal mucosal injury. |
Databáze: |
Complementary Index |
Externí odkaz: |
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