Bis(indoline-2,3-diones): versatile precursors for novel bis(spirooxindoles) incorporating 4 H-chromene-3-carbonitrile and pyrano[2,3-d]pyrimidine-6-carbonitrile derivatives.
Autor: | GHOZLAN, Said Ahmed Soliman, RAMADAN, Muhammed Aly, ABDELMONIEM, Amr Mohamed, ELWAHY, Ahmed H. M., ABDELHAMID, Ismail Abdelshafy |
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Zdroj: | Turkish Journal of Chemistry; 2017, Vol. 41 Issue 3, p410-419, 10p |
Abstrakt: | Multicomponent reaction of dimedone or 1,3-dimethylbarbituric acid and malononitrile with a series of bis(indoline-2,3-diones) afforded the corresponding bis(2-amino-7,7-dimethyl-2',5-dioxo-5,6,7,8-tetrahydrospiro[chromene-4,3'-indoline]-3-carbonitrile) and bis(7'-amino-1',3'-dimethyl-2,2',4'-trioxo-1',2',3',4'-tetrahydrospiro[indoline-3,5'-pyrano [2,3-d]pyrimidine]-6'-carbonitrile) derivatives in good to excellent yield. [ABSTRACT FROM AUTHOR] |
Databáze: | Complementary Index |
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