| Autor: |
Berraho, Mohamed, Amarti-Riffi, Afaf, El-Mzibri, Mohammed, Bezad, Rachid, Benjaafar, Noureddine, Benideer, Abdelatif, Matar, Noureddine, Qmichou, Zinab, Abda, Naima, Attaleb, Mohammed, Znati, Kaoutar, El Fatemi, Hind, Bendahhou, Karima, Obtel, Majdouline, Adib, Abdelhai Filali, Mathoulin-Pelissier, Simone, Nejjari, Chakib, Filali Adib, Abdelhai |
| Předmět: |
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| Zdroj: |
BMC Cancer; 6/20/2017, Vol. 17, p1-9, 9p, 6 Charts |
| Abstrakt: |
Background: Limited national information is available in Morocco on the prevalence and distribution of HPV-sub-types of cervical cancer and the role of other risk factors. The aim was to determine the frequency of HPV-sub-types of cervical cancer in Morocco and investigate risk factors for this disease.Methods: Between November 2009 and April 2012 a multicentre case-control study was carried out. A total of 144 cases of cervical cancer and 288 age-matched controls were included. Odds-ratios and corresponding confidence-intervals were computed by conditional logistic regression models.Results: Current HPV infection was detected in 92.5% of cases and 13.9% of controls. HPV16 was the most common type for both cases and controls. Very strong associations between HPV-sub-types and cervical cancer were observed: total-HPV (OR = 39), HPV16 (OR = 49), HPV18 (OR = 31), and multiple infections (OR = 13). Education, high parity, sexual intercourse during menstruation, history of sexually transmitted infections, and husband's multiple sexual partners were also significantly associated with cervical cancer in the multivariate analysis.Conclusions: Our results could be used to establish a primary prevention program and to prioritize limited screening to women who have specific characteristics that may put them at an increased risk of cervical cancer. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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