| Autor: |
Stein, D. J., Hollander, E., Mullen, L. S., Decaria, C. M., Liebowitz, M. R. |
| Předmět: |
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| Zdroj: |
Human Psychopharmacology: Clinical & Experimental; Nov/Dec92, Vol. 7 Issue 6, p389-395, 7p |
| Abstrakt: |
Forty-four patients with obsessive-compulsive disorder (OCD) were entered into a double-blind randomly assigned treatment protocol with clomipramine (CMI) or placebo. In addition, alprazolam was administered to 14 OCD patients in a separate open-treatment study. The response rate of patients completing treatment was 50 per cent with CMI, 19 per cent with placebo, and 18 per cent with alprazolam. Self-ratings of obsessive-compulsive symptoms in intent to treat and completer samples demonstrated a significantly greater benefit with CMI than with alprazolam. Ratings of depression and clinician ratings of obsessionality in both intent-to-treat and completer samples did not, however, indicate differences between the treatment groups. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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