| Autor: |
Low, Andrea, Xin, Xiaohui, Law, Weng, Teng, Gim, Santosa, Amelia, Lim, Anita, Chan, Grace, Ng, Swee, Thumboo, Julian |
| Předmět: |
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| Zdroj: |
Clinical Rheumatology; Jul2017, Vol. 36 Issue 7, p1643-1648, 6p, 4 Charts |
| Abstrakt: |
The aim of this study was to (1) translate the Gastrointestinal Tract Instrument (GIT) 2.0 from English to Chinese and (2) validate both versions in a multi-ethnic systemic sclerosis cohort in Singapore (SCORE). The English GIT2.0 was translated to Chinese using a standard forward-backward translation approach. Psychometric evaluation of the GIT2.0 included internal consistency reliability (using Cronbach's alpha), test-retest reliability (using intra-class correlation coefficient (ICC)), scale level factor analysis, and construct validity (using Spearman correlation) against the modified Scleroderma Health Assessment Questionnaire (S-HAQ) and the SF-36 v2. Most of the patients were females (88.6%) and Chinese (78.2%), with mean (SD) age of 51.0 (13.0) years and median disease duration of 4.5 years. We administered English ( n = 146) and Chinese ( n = 74) GIT2.0. The mean (SD) total GIT score was 0.29 (0.37). There was good internal consistency (Cronbach's alpha >0.70 for all subscales) and good test-retest reliability for the scale and all subscales (ICC 0.71-0.92) except for 'diarrhoea' (ICC = 0.54). Our hypothesised a priori construct validity was supported by moderate correlations between the total GIT score and S-HAQ GI subscale ( r = 0.446), and the social functioning subscale and SF36v2 role-social domain ( r = 0.337), and weak-to-moderate correlation between the emotional subscale and SF-36v2 role-emotional ( r = 0.295) and mental health ( r = 0.298) domains and mental component summary ( r = 0.356). Exploratory factor analysis of the seven subscales yielded a two-factor solution explaining 69.63% of the total variance. This study provides evidence for the reliability and validity of the English and Chinese GIT2.0 to be used in Singapore for research and routine practice. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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