Autor: |
Hegeman, Johanna M., Fenema, Esther M., Comijs, Hannie C., Kok, Rob M., Mast, Roos C., Waal, Margot W.M., van Fenema, Esther M, van der Mast, Roos C, de Waal, Margot W M |
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Zdroj: |
International Journal of Geriatric Psychiatry; Jul2017, Vol. 32 Issue 7, p779-787, 9p, 3 Charts, 1 Graph |
Abstrakt: |
Objective: To examine the influence of specific chronic somatic diseases and overall somatic diseases burden on the course of depression in older persons.Methods: This was a prospective cohort study with a 2-year follow-up. Participants were depressed persons (n = 285) from the Netherlands Study of Depression in Older Persons. The presence of chronic somatic diseases was based on self-report. Diagnosis of depression was assessed with the Composite International Diagnostic Interview, and severity of depression was measured with the Inventory of Depressive Symptomatology Self-report.Results: Cardiovascular diseases (odds ratio [OR] = 1.67, 95% confidence interval [CI] = 1.02-2.72, p = 0.041), musculoskeletal diseases (OR = 1.71, 95% CI = 1.04-2.80, p = 0.034), and the number of chronic somatic diseases (OR = 1.37, 95% CI = 1.16-1.63, p < 0.001) were associated with having a depressive disorder at 2-year follow-up. Furthermore, chronic non-specific lung diseases, cardiovascular diseases, musculoskeletal diseases, cancer, or cumulative somatic disease burden were associated with a chronic course of depression.Conclusions: Somatic disease burden is associated with a poor course of late-life depression. The course of late-life depression is particularly unfavorable in the presence of chronic non-specific lung diseases, cardiovascular diseases, musculoskeletal diseases, and cancer. Copyright © 2016 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
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