| Autor: |
Saracli, M. A., Erdem, U., Gonlum, A., Yildiran, S. T. |
| Předmět: |
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| Zdroj: |
Medical Mycology; Apr2003, Vol. 41 Issue 2, p111-114, 4p, 4 Color Photographs |
| Abstrakt: |
Mycotic keratitis usually occurs in conjunction with trauma to the cornea. Scedosporium apiospermum , a dematiaceous fungus linked to the teleomorph Pseudallescheria boydii is not a common agent of mycotic keratitis. A 22-year old male patient with mycotic keratitis due to S. apiospermum is presented. In in vitro susceptibility testing, the isolate showed resistance against amphotericin B (minimum inhibitory concentration [MIC] 16 µg ml -1 ) but was susceptible to itraconazole (ITC) and fluconazole with MICs of 0.125 µg ml -1 and 4 µg ml -1 , respectively. The patient was cured clinically after ITC treatment and surgical intervention. Azoles may be superior for eliminating S. apiospermum from infected ocular sites. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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