A New Method for Measuring Progression in Patients With Ocular Cicatricial Pemphigoid.

Autor: Rowsey, J. James, Macias-Rodriguez, Yolanda, Cukrowski, Chris
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Zdroj: Archives of Ophthalmology; Feb2004, Vol. 122 Issue 2, p179-184, 6p
Abstrakt: Objectives: To describe a method to measure the progression of ocular cicatricial pemphigoid and to compare its facility with traditional methods used to measure the progression of the disease. Methods: The proposed method consists of measuring (in millimeters) the total relative inferior conjunctival surface available in 3 gaze positions. This method was used to monitor 7 eyes of 4 patients with ocular cicatricial pemphigoid over 2 years. The changes in the conjunctival measurements from baseline were compared with the changes documented by traditional methods. Results: During the study, 2 eyes remained stable (changes, <3 mm), 2 had a decrease of 10 mm or more, and 3 had a change in measurements between 4 and 9 mm. With the proposed method, we demonstrated the detection of more subtle changes in the conjunctiva of all patients. Patients who had changes between 4 and 9 mm easily underwent staging by the traditional systems when the new technique was used as a reference. Conclusion: The proposed method offers an objective variable that can be used in consecutive visits to detect subtle progression or disease control in patients with ocular cicatricial pemphigoid. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index