Swelling Characteristics and Drug Release Kinetics of Ag/PVA Hydrogel Nanocomposites.

Autor: K., Swaroop, H. M., Somashekarappa
Předmět:
Zdroj: AIP Conference Proceedings; 2017, Vol. 1832 Issue 1, p1-3, 3p, 1 Black and White Photograph, 1 Chart, 4 Graphs
Abstrakt: Ag/PVA hydrogels nanocomposites (HNC's) of different Ag concentrations were synthesized using gamma irradiation technique. The prepared hydrogels were characterized using powder XRD, UV, SEM and TEM analysis. The equilibrium and dynamic swelling properties of different concentrations of Ag/PVA HNC's were studied. It has been observed that the swelling properties of the Ag/PVA HNC's increase with the Ag concentration. L-ascorbic acid was loaded to Ag/PVA HNC's and the release data was monitored by the absorption wavelength at 252 nm. The results indicate that both swelling and the ascorbic acid release process of Ag/PVA HNC's follows non-Fickian mechanism. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index