Parasitological, bacteriological and in-vitro studies on antibacterial activity of ethanolic extract of Calligonumcomosum in goats affected with fascioliasis in Taif, KSA.

Autor: Nabila, S. Degheidy, Gamila, S. Al-Malki, Fatimah, S. Al-Harbi
Předmět:
Zdroj: International Journal of Pharmaceutical Research & Allied Sciences; 2017, Vol. 6 Issue 2, p37-48, 12p
Abstrakt: This study was carried out to detect the relationship between bacterial infections and liver fascioliasis. Grossly, post mortem examination of the livers infested with Fasciolagigantica in the present study, were hard, firm and tough in consistency with multiple, irregular pale brownish areas on the surface. Cut section of the liver revealed presence of large whitish areas of fibrosis. The affected ducts were enlarged, thickened, hard in consistency and in the form of cord like structures and protruded above the surface of the liver. In most cases, mature Fasciola worms were detected within the lumen of the affected bile ducts and bile stones. Several types of bacteria were isolated from liver surface, bile duct and Fasciola worms from goats suffering from chronic fascioliasis. Bacterial isolated from liver surface were Stenotrophomonasmalyophilia, Corynebacteriumpropinquum and Escherichia coli. The bacteriological bile culture, revealed isolation of AerococcusUrinae and Escherichia coli. While bacterial species isolated from Fasciolagigantica, were Leifsonia aquatic, Corynebacteriumrenale group, Corynebacterium species, Escherichia coli and Lactococcuslactis spp. cremoris. All the isolated microorganisms are pathogenic and can transmitted from animals to human causing very dangerous zoonotic diseases. The present investigation evaluated the in-vitro antibacterial activity of the crude ethanolic extracts of Calligonumcomosum 10% on some gram positive and negative bacteria. Further in vivo studies are required to validate our findings and improve our knowledge on the potential of the Calligonumcomosum extract as antimicrobial in relation to its chemical composition. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index