Photo-cleavable analog of BAPTA for the fast and efficient release of Ca2+.

Autor: Sutton, Mariia V., McKinley, Matthew, Kulasekharan, Revathy, Popik, Vladimir V.
Předmět:
Zdroj: Chemical Communications; 5/21/2017, Vol. 53 Issue 41, p5598-5601, 4p
Abstrakt: A new photocleavable analog of BAPTA chelating ligand has a high affinity towards Ca2+ ions (K = 2.5 × 106 M−1). The use of photolabile 3-(hydroxymethyl)-2-naphthol core in the design of photo-BAPTA allows for the efficient (Φ = 0. 63) and very fast (τ < 12 μs) release of Ca2+ ions upon 300 or 350 nm irradiation. [ABSTRACT FROM AUTHOR]
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