| Autor: |
Khan, Nadia A., Daskalopoulou, Stella S., Karp, Igor, Eisenberg, Mark J., Pelletier, Roxanne, Tsadok, Meytal Avgil, Dasgupta, Kaberi, Norris, Colleen M., Pilote, Louise, GENESIS PRAXY Team |
| Předmět: |
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| Zdroj: |
Heart; Jun2017, Vol. 103 Issue 11, p863-869, 7p, 1 Diagram, 5 Charts, 1 Graph |
| Abstrakt: |
Background: Studies suggest that young women are at highest risk for failing to recognise early symptoms of acute coronary syndrome (ACS).Objectives: To examine sex differences in prodromal symptoms occurring days and weeks prior to the acute presentation of ACS. We also examined health-seeking behaviours and prehospital management in young patients.Methods: Prospective cross-sectional analysis of 1145 patients (368 women) hospitalised for ACS, aged ≤55 years, from the GENdEr and Sex DetermInantS of Cardiovascular Disease: From Bench to Beyond Premature Acute Coronary SYndrome cohort study (January 2009-April 2013). Prodromal symptoms were determined using the McSweeney Acute and Prodromal Myocardial Infarction Symptom questionnaire. Health-seeking behaviour and prehospital care were determined by questionnaires.Results: The median age was 49 years. The prevalence of prodromal symptoms was high and more women reported symptoms than men (85% vs 72%, p<0.0001). Symptoms were similar between sexes and included unusual fatigue, sleep disturbances, anxiety and arm weakness/discomfort. Chest pain was less common in both sexes (24%). Women were more likely to seek care (49% vs 42%, p=0.04). Among those who sought care, women were more likely to use an ambulance for their ACS compared with men (52% vs 39%). Cardiovascular risk-reduction therapy use was low (≤40%) in all patients and less than half perceived their care provider suspected a cardiac source.Conclusions: Prior to ACS, women were more likely to experience prodromal symptoms and seek medical attention than men. Prehospital care was generally similar between sexes but demonstrated underutilisation of risk-reduction therapies in at-risk young adults. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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