| Autor: |
Ramos Silva, Jean Carlos, Ferreira, Fernando, Augusto Dias, Ricardo, Ajzenberg, Daniel, Vianna Marvulo, Maria Fernanda, Rodrigues Magalhães, Fernando Jorge, Ferreira Lima Filho, Carlos Diógenes, Oliveira, Solange, Sousa Soares, Herbert, Ferreira Feitosa, Thais, Aizawa, Juliana, Câmara Alves, Leucio, Aparecido Mota, Rinaldo, Prakask Dubey, Jitender, Gennari, Solange Maria, Jesus Pena, Hilda Fátima |
| Předmět: |
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| Zdroj: |
Parasites & Vectors; 5/3/2017, Vol. 10, p1-6, 6p |
| Abstrakt: |
Background: In Brazil, studies on animals and humans in mainland areas have shown that most strains of Toxoplasma gondii are pathogenic to mice and exhibit great genetic variability. Results: In this study, using a set of 11 PCR-RFLP and 15 microsatellite markers, we isolated and genetically characterised T. gondii strains from one cat and three rats on Fernando de Noronha Island. The cat had antibodies to T. gondii, which were revealed using a modified agglutination test (MAT, cut-off 1:25) and the seroprevalence among the 46 rodents was 15.2%. Viable T. gondii was isolated from one cat (TgCatBrFN1), two brown rats (TgRatnoBrFN1 and TgRatnoBrFN2) and one black rat (TgRatraBrFN1). Unlike the strains from mainland Brazil, these isolates were not pathogenic to outbred mice. The genotypes of these strains were compared with strains previously isolated on the island and in mainland Brazil. The analysis based on microsatellite data showed a limited genetic diversity of T. gondii on Fernando de Noronha Island with the majority of strains clustered into the following three groups: type II, III, and Caribbean 1. Conclusions: There was little variation among strains within the same group, suggesting that the majority of strains circulating on Fernando de Noronha are derived from only a few strains that were recently introduced to the island, likely from imported cats. Except for the strain belonging to the Caribbean 1 group that originates from northeast Brazil, there was little evidence that strains from the other groups were introduced to Fernando de Noronha via mainland Brazil. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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