Association of BMI with risk of CVD mortality and all-cause mortality.

Autor: Kee, Chee Cheong, Sumarni, Mohd Ghazali, Lim, Kuang Hock, Selvarajah, Sharmini, Haniff, Jamaiyah, Tee, Guat Hiong Helen, Gurpreet, Kaur, Faudzi, Yusoff Ahmad, Amal, Nasir Mustafa
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Zdroj: Public Health Nutrition; May2017, Vol. 20 Issue 7, p1226-1234, 9p
Abstrakt: Objective: To determine the relationship between BMI and risk of CVD mortality and all-cause mortality among Malaysian adults.Design: Population-based, retrospective cohort study. Participants were followed up for 5 years from 2006 to 2010. Mortality data were obtained via record linkages with the Malaysian National Registration Department. Multiple Cox regression was applied to compare risk of CVD and all-cause mortality between BMI categories adjusting for age, gender and ethnicity. Models were generated for all participants, all participants the first 2 years of follow-up, healthy participants, healthy never smokers, never smokers, current smokers and former smokers.Setting: All fourteen states in Malaysia.Subjects: Malaysian adults (n 32 839) aged 18 years or above from the third National Health and Morbidity Survey.Results: Total follow-up time was 153 814 person-years with 1035 deaths from all causes and 225 deaths from CVD. Underweight (BMI<18·5 kg/m2) was associated with a significantly increased risk of all-cause mortality, while obesity (BMI ≥30·0 kg/m2) was associated with a heightened risk of CVD mortality. Overweight (BMI=25·0-29·9 kg/m2) was inversely associated with risk of all-cause mortality. Underweight was significantly associated with all-cause mortality in all models except for current smokers. Overweight was inversely associated with all-cause mortality in all participants. Although a positive trend was observed between BMI and CVD mortality in all participants, a significant association was observed only for severe obesity (BMI≥35·0 kg/m2).Conclusions: Underweight was associated with increased risk of all-cause mortality and obesity with increased risk of CVD mortality. Therefore, maintaining a normal BMI through leading an active lifestyle and healthy dietary habits should continue to be promoted. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index