| Autor: |
Klinghoffer, Richard A., Bahrami, S. Bahram, Hatton, Beryl A., Frazier, Jason P., Moreno-Gonzalez, Alicia, Strand, Andrew D., Kerwin, William S., Casalini, Joseph R., Thirstrup, Derek J., Sheng You, Morris, Shelli M., Watts, Korashon L., Veiseh, Mandana, Grenley, Marc O., Tretyak, Ilona, Dey, Joyoti, Carleton, Michael, Beirne, Emily, Pedro, Kyle D., Ditzler, Sally H. |
| Předmět: |
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| Zdroj: |
Science Translational Medicine; 4/22/2015, Vol. 7 Issue 284, p1-12, 12p, 4 Color Photographs, 23 Graphs |
| Abstrakt: |
The article focuses findings of a study on a technology platform to assess multiple cancer agents simultaneously within a patient's tumor. It states that the platform called CIVO, which enables simultaneous assessment of up to eight drugs or drug combinations within a single solid tumor in vivo, and mentions that observed localized responses predicted responses to systemically delivered drugs in animals. It infers that CIVO demonstrated that microinjection of drugs is toxicity-sparing. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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