Long-lasting stem cell–like memory CD8+ T cells with a naïve-like profile upon yellow fever vaccination.

Autor: Marraco, Silvia A. Fuertes, Soneson, Charlotte, Cagnon, Laurène, Gannon, Philippe O., Allard, Mathilde, Maillard, Samia Abed, Montandon, Nicole, Rufer, Nathalie, Waldvogel, Sophie, Delorenzi, Mauro, Speiser, Daniel E.
Předmět:
Zdroj: Science Translational Medicine; 4/8/2015, Vol. 7 Issue 282, p1-14, 14p, 1 Chart, 6 Graphs
Abstrakt: The article looks at a study by stem cell–like memory CD8 T cells with a naïve-like profile upon yellow fever vaccination and long-term protection from infectious and malignant diseases. It mentions analysis of markers and genome-wide mRNA profiling and stem cell–like memory subset and induced by a vaccine in humans. It also mentions conventional references include the lifelong persisting herpes viruses cytomegalovirus (CMV) and Epstein-Barr virus (EBV) and seasonal influenza.
Databáze: Complementary Index