| Autor: |
Lihua Ying, Becard, Margaux, Lyell, Deirdre, Xiaoyuan Han, Linda Shortliffe, Husted, Cristiana Iosef, Alvira, Cristina M., Cornfield, David N. |
| Předmět: |
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| Zdroj: |
Science Translational Medicine; 12/23/2015, Vol. 7 Issue 319, p1-11, 11p, 3 Color Photographs, 3 Graphs |
| Abstrakt: |
The article focuses findings of a study on role of the transient receptor potential vanilloid 4 channel in modulating uterine tone during pregnancy. It states that smooth muscle cells (mSMCs), TRPV4 gene and protein expression increased with gestation, and TRPV4-mediated Ca2+ entry and contractility were increased in mSMC from pregnant compared to nonpregnant rats, and mentions Cell membrane TRPV4 expression was increased. It infers that TRPV4 activity modulates uterine contractility. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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