| Autor: |
Andrews, Chasity D., Yun Lan Yueh, Spreen, William R., Bernard, Leslie St., Boente-Carrera, Mar, Rodriguez, Kristina, Gettie, Agegnehu, Russell-Lodrigue, Kasi, Blanchard, James, Ford, Susan, Mohri, Hiroshi, Cecilia Cheng-Mayer, Zhi Hong, Ho, David D., Markowitz, Martin |
| Předmět: |
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| Zdroj: |
Science Translational Medicine; 1/14/2015, Vol. 7 Issue 270, p1-9, 9p, 1 Diagram, 1 Chart, 2 Graphs |
| Abstrakt: |
The article presents a research investigating how long-acting integrase inhibitor GSK1265744 protects female macaques from repeated high-dose intravaginal simian-human immunodeficiency virus (SHIV). It mentions that GSK1265744 acts as an effective preexposure prophylaxis (PrEP) agent in a low-dose intrarectal SHIV. It concludes that GSK744 LA treatment protected six of eight in Depo-Provera–treated female rhesus macaques against three high-dose SHIV. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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