Oncogenic Osteomalacia: An Approach to Diagnosis with a Case Report.

Autor: DEY, BISWAJIT, GOCHHAIT, DEBASIS, SUBRAMANIAN, HEMA, PONNUSAMY, MADHUSUDHANAN
Předmět:
Zdroj: Journal of Clinical & Diagnostic Research; Apr2017, Vol. 11 Issue 4, p5-7, 3p
Abstrakt: Oncogenic osteomalacia, also known as tumour induced osteomalacia, is a rare paraneoplastic syndrome caused by mesenchymal tumours secreting Fibroblast Growth Factor-23 (FGF-23). The characteristic biochemical findings include hypophosphatemia and low 1,25-dihydroxy vitamin D. The differential diagnosis for hypophosphatemia are varied. We present a case of oncogenic osteomalacia in a 29-year-old female, who presented with complaints of generalized diffuse bone pain and walking difficulty for six months duration. Thus, we have discussed the approach to diagnosis in such a case. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index