Autor: |
Gendron, Tania F., Chew, Jeannie, Stankowski, Jeannette N., Hayes, Lindsey R., Yong-Jie Zhang, Prudencio, Mercedes, Carlomagno, Yari, Daughrity, Lillian M., Jansen-West, Karen, Perkerson, Emilie A., O'Raw, Aliesha, Cook, Casey, Pregent, Luc, Belzil, Veronique, van Blitterswijk, Marka, Tabassian, Lilia J., Lee, Chris W., Mei Yue, Jimei Tong, Yuping Song |
Předmět: |
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Zdroj: |
Science Translational Medicine; 3/29/2017, Vol. 9 Issue 383, p1-12, 12p |
Abstrakt: |
The article discusses the usefulness of Poly(GP) proteins in pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis. It cites on the progressive motor neuron disease which results into muscle atrophy, paralysis and death after 5 years of onset. The article also discusses the drug approval of riluzole, citing its clinical trials conducted since 1995. |
Databáze: |
Complementary Index |
Externí odkaz: |
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