| Autor: |
Balko, Justin M., Schwarz, Luis J., Na Luo, Estrada, Mónica V., Giltnane, Jennifer M., Dávila-González, Daniel, Kai Wang, Sánchez, Violeta, Dean, Phillip T., Combs, Susan E., Hicks, Donna, Pinto, Joseph A., Landis, Melissa D., Doimi, Franco D., Yelensky, Roman, Miller, Vincent A., Stephens, Phillip J., Rimm, David L., Gómez, Henry, Chang, Jenny C. |
| Předmět: |
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| Zdroj: |
Science Translational Medicine; 4/13/2016, Vol. 8 Issue 334, p1-11, 11p, 5 Color Photographs, 2 Charts |
| Abstrakt: |
The article presents research demonstrating Janus kinase 2 (JAK2) gene dependence of triple-negative breast cancers with JAK2 amplification. Topics discussed include the identification of JAK2 amplifications in breast cancer, the attribution of phenotypes to a cell population, and the potential of JAK2 amplification as JAK2 dependence biomarker. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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