| Autor: |
Olopade, B. O., Ogunniyi, T. A., Oyekunle, A. A., Odetoyin, B. W., Adegoke, A. O. |
| Předmět: |
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| Zdroj: |
International Journal of Medicine & Biomedical Research; Jan-Apr2017, Vol. 6 Issue 1, p18-29, 12p |
| Abstrakt: |
Background: Cryptosporidiosis is a parasitic disease which has assumed importance because of its increased incidence in immunocompromised states. Aim: The study determined the prevalence of cryptosporidiosis in adult HIV-infected patients and assessed risk factors predisposing to the development of cryptosporidial infection in these patients. The study also compared microscopy and the use of cryptosporidial antigen detection kit in the diagnosis of cryptosporidiosis. Methods: This cross-sectional study involved two hundred and twenty six patients that attended the virology research clinic, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife. Questionnaires were administered to obtain relevant demographic information. Stool samples were collected into universal bottles and processed using the Modified Ziehl-Neelson staining procedure and Cryptosporidium antigen detection kit (Cryptostrip kit). Data entry and processing were done using the computer software SPSS version 17 and analysed using descriptive and inferential statistics. Results: The results showed that of the 226 patients that participated in the study, ten (4.4%) had cryptosporidiosis. Cryptosporidiosis was significantly associated with exposure to dogs (χ2 = 6.904, p = 0.009), exposure to goats (χ2 = 8.685, p= 0.003) and being an artisan (OR 4.02, C.I =0.88-8.99, p= 0.023. Other factors considered were not significantly associated. Conclusion: This study concluded that elderly HIV-infected patients on highly active anti-retroviral therapy still have a risk of acquisition of cryptosporidiosis particularly when exposed to dogs and goats and by being an artisan. There is a need to educate these patients on sanitary disposal of faeces, washing of hands and maintaining high level of hygiene. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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