| Autor: |
Morrison, Eliot, Wiedemann, Hannah, Brügger, Britta, Freund, Christian |
| Zdroj: |
BioSpektrum; Feb2017, Vol. 23 Issue 1, p32-35, 4p |
| Abstrakt: |
The covalent attachment of lipid moieties to proteins represents an important subclass of co- or post-translational modifications in the cell. The 16-carbon fully saturated lipid palmitate is preferentially conjugated to free cysteines of peripheral or integral membrane proteins. The thioester bond formed can be reversibly hydrolyzed and thereby modulates a proteins function with regard to trafficking, compartmentation within the membrane or lipid-induced conformational changes in a cyclic manner. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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