| Autor: |
Whitmore, T. E., Maurer, M. F., Day, H. L., Jelmberg, A. C., Dasovich, M. M., Sundborg, L. M., Burkhead, S. K., Heipel, M. D., Madden, K. L., Kramer, J. M., Kuijper, J. L., Xu, W. F., Jaspers, S. R., Holly, R. D., Lok, S. |
| Předmět: |
|
| Zdroj: |
Cytogenetics & Cell Genetics; Oct99, Vol. 87 Issue 1/2, p93-94, 2p |
| Abstrakt: |
The insulin receptor-related receptor (INSRR) was first identified as a genomic sequence encoding a novel member of the insulin receptor family. Unlike other members of the receptor family, the expression of INSRR is relatively restricted. INSRR mRNA and protein are localized in subsets of neuron, in renal distal tubules and in the enterochromaffin-like cells of the fundic stomach. Most recently, expression of INSRR was found in the islets of Langerhans suggesting INSRR may be involved in the physiological functions of insulin-secreting cells. Previously, the INSRR locus was localized to chromosome 1 by the use of a human hamster somatic cell panel. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
