Enhanced cAMP accumulation by the human thyrotropin receptor variant with the Pro52Thr substitution in the extracellular domain.

Autor: Loos, Ulrich, Hagner, Stefanie, Bohr, Ulrich R.M., Bogatkewitsch, Galina S., Jakobs, Karl H., Van Koppen, Chris J.
Předmět:
Zdroj: European Journal of Biochemistry; 8/15/95, Vol. 232 Issue 1, p62-65, 4p
Abstrakt: Studies the enhanced cyclic adenylic acid (cAMP) accumulation by the human thyrotropin receptor variant with the Pro52Thr substitution in the extracellular domain. Variant and wild-type receptors; Increase in cAMP accumulation due to thyrotropin; Role of hyperactive thyrotropin receptor in hyperthyroidism of patients with Graves' disease.
Databáze: Complementary Index