Successful treatment without cranial radiotherapy of children receiving intensified chemotherapy for acute lymphoblastic leukaemia: results of the risk-stratified randomized central nervous system treatment trial MRC UKALL XI (ISRC TN 16757172).

Autor:	Hill, Frank G.H., Richards, Sue, Gibson, Brenda, Hann, Ian, Lilleyman, John, Kinsey, Sally, Mitchell, Christopher, Harrison, Christine J., Eden, Osborn B.
Předmět:	CENTRAL nervous system LYMPHOBLASTIC leukemia in children METHOTREXATE LEUCOCYTES RADIOTHERAPY DISEASE relapse
Zdroj:	British Journal of Haematology; Jan2004, Vol. 124 Issue 1, p33-46, 14p, 5 Charts, 4 Graphs
Abstrakt:	Explores the results of Medical Research Center UKALI XI's risk-stratified randomized central nervous system treatment trial of children with acute lymphoblastic leukemia (ALL). Isolated central nervous system (CNS) relapse rate; Comparison between high dose intravenous methotrexate and intrathecal methotrexate; Effectiveness of CNS-directed therapy within the white blood cell.
Databáze:	Complementary Index
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