| Autor: |
Christensen, Mike T., Rinehart, John, Akers, Frank, Pemberton, Bart, Bloomenstein, Marc, Kaplan, David, Meadows, David, Meuse, Patricia, Hearn, Charles, Stein, Jerry M., Cohen, Steven, Lesher, Mark |
| Předmět: |
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| Zdroj: |
Current Eye Research; Jan2004, Vol. 28 Issue 1, p55-62, 8p, 3 Charts, 8 Graphs |
| Abstrakt: |
Purpose. To evaluate the efficacy of a new lubricant eye drop containing polyethylene glycol 400 and propylene glycol demulcents with hydroxypropyl-guar as a gelling agent (Test Product) to a system with carboxymethylcellulose (Control Product) for reducing dry eye signs and symptoms. Methods. Eighty-seven dry eye volunteers were enrolled at seven sites for this six-week, concurrently controlled, double-masked clinical study. Results. The Test Product significantly reduced conjunctiva! staining (p = 0.025) and temporal corneal staining (p = 0.024) compared to the Control. The Test Product also significantly reduced symptoms of dryness in the morning and evening, compared to the Control (p = 0.015 and p = 0.023, respectively). Subjects in the Test treatment group reported lower frequencies of foreign body sensation and fell their eyes were "refreshed longer" compared to those in the Control group (p = 0.033 and p = 0.037, respectively). Conclusions. The Test Product was more effective at reducing both the signs and symptoms of dry eye compared to the carboxymethylcellulose containing Control. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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