| Autor: |
Villarreal, Ithzel M., Arellano, Beatriz, Pinilla, Mayte, Tejerina, E, López-Cortijo, Cristóbal |
| Předmět: |
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| Zdroj: |
Acta Oto-Laryngologica Case Reports; Dec2016, Vol. 1 Issue 1, p63-66, 4p |
| Abstrakt: |
Small-cell neuroendocrine carcinoma (SNEC) is a distinct tumoral entity characterized by rapid local invasion, widespread dissemination and a poor prognosis. Due to its late discovery, localization is rarely precise. We report a case of a 39-year-old man whose clinical symptoms, radiological findings histological diagnosis and immunohistochemical staining confirm a primary SNEC of the nasal septum. Clinical features of nasal SNEC are nonspecific, including those resembling benign lesions; hence, it is likely to result in a delay in its discovery and treatment. Distinction between SNEC and other neuroendocrine tumors is also of great importance because of its prognostic implication, being SNEC the most aggressive in this group. Surgery, radiotherapy and chemotherapy alone or in combination have been used for these patients. Unfortunately, due to the rarity of this neoplasm, there is no specific recommendation on management guidelines, and treatment possibilities should be individualized for each patient. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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