Options for basing Dietary Reference Intakes (DRIs) on chronic disease endpoints: report from a joint US-/Canadian-sponsored working group.
Autor: | Yetley, Elizabeth A., MacFarlane, Amanda J., Greene-Finestone, Linda S., Garza, Cutberto, Ard, Jamyy D., Atkinson, Stephanie A., Bier, Dennis M., Carriquiry, Alicia L., Harlan, William R., Hattis, Dale, King, Janet C., Krewski, Daniel, O'Connor, Deborah L., Prentice, Ross L., Rodricks, Joseph V., Wells, George A. |
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Předmět: |
CHRONIC diseases
DIET DISEASES in older people PREVENTION of chronic diseases NUTRITION GERIATRIC nutrition CHRONIC disease treatment NUTRITION policy SYSTEMATIC reviews RESEARCH methodology evaluation CONCEPTUAL structures CHRONIC disease risk factors DECISION making DIETETICS research DOSE-response relationship in biochemistry EXPERIMENTAL design MEDICINE information services META-analysis NUTRITIONAL requirements OBESITY SCIENTIFIC observation PUBLIC health REFERENCE values STATISTICS EVIDENCE-based medicine PROFESSIONAL practice DATA analysis RANDOMIZED controlled trials RESEARCH bias HEALTH information services EVALUATION |
Zdroj: | American Journal of Clinical Nutrition; 1/1/2017, Vol. 105 Issue 1, p249S-285S, 37p, 3 Diagrams, 10 Charts, 2 Graphs |
Abstrakt: | Dietary Reference Intakes (DRIs) are used in Canada and the United States in planning and assessing diets of apparently healthy individuals and population groups. The approaches used to establish DRIs on the basis of classical nutrient deficiencies and/or toxicities have worked well. However, it has proved to be more challenging to base DRI values on chronic disease endpoints; deviations from the traditional framework were often required, and in some cases, DRI values were not established for intakes that affected chronic disease outcomes despite evidence that supported a relation. The increasing proportions of elderly citizens, the growing prevalence of chronic diseases, and the persistently high prevalence of overweight and obesity, which predispose to chronic disease, highlight the importance of understanding the impact of nutrition on chronic disease prevention and control. A multidisciplinary working group sponsored by the Canadian and US government DRI steering committees met from November 2014 to April 2016 to identify options for addressing key scientific challenges encountered in the use of chronic disease endpoints to establish reference values. The working group focused on 3 key questions: 1) What are the important evidentiary challenges for selecting and using chronic disease endpoints in future DRI reviews, 2) what intake-response models can future DRI committees consider when using chronic disease endpoints, and 3) what are the arguments for and against continuing to include chronic disease endpoints in future DRI reviews? This report outlines the range of options identified by the working group for answering these key questions, as well as the strengths and weaknesses of each option. [ABSTRACT FROM AUTHOR] |
Databáze: | Complementary Index |
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