| Autor: |
Faisant, Charles, Thanh, Aurélie, Mansard, Catherine, Deroux, Alban, Boccon-Gibod, Isabelle, Bouillet, Laurence |
| Předmět: |
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| Zdroj: |
Journal of Clinical Immunology; Jan2017, Vol. 37 Issue 1, p80-84, 5p |
| Abstrakt: |
Idiopathic non-histaminergic acquired angioedema (InH-AAE) is a rare disease characterized by AE resistant to antihistamines and a chronic course. We report five new cases of InH-AAE (two women and three men) with a rapid and dramatic response to the anti-immunoglobulin-E antibody omalizumab. In our literature review, we found 13 other relevant cases with a good response to this treatment. Overall, in 6 out of 18 patients, the doses of omalizumab required to prevent recurrences of attacks were higher than the licensed dose for chronic urticaria. No significant adverse effects have been reported. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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