| Autor: |
Nakai, Yoshikatsu, Kinoshita, Fumiko, Koh, Toshikiyo, Tsujii, Satoru, Isukada, Toshihiko |
| Předmět: |
|
| Zdroj: |
International Journal of Eating Disorders; Jan1987, Vol. 6 Issue 1, p49-57, 9p |
| Abstrakt: |
The effect of intracellular glucopenia induced by 2-deoxy-Doglucose (2-DG) on changes in hunger ratings, blood glucose, plasms cortisol, and prolactin levels were examined in six female patients with primary anorexia nervosa, three patients with bulimia nervosa, and six age- and sex-matched volunteers. In the normal subjects, hunger ratings obtained by the linear visual analog technique increased significantly at 60 minutes after 2-DG infusion and remained elevated. In patients with anorexia nervosa, however, hunger ratings paradoxically decreased significantly at 90 minutes. In normal subjects, the ingestion of a 20-minute lunch relieved hunger, but neither the anorexic patients nor bulimic patients felt satiety even after food intake. These results suggest that the perception of hunger induced by 2-DG in anorexia nervosa and that of satiety in anorexia nervosa and bulimia nervosa are disturbed. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
