Angiofibroma of Soft Tissue on the Cheek: Diagnosis Confirmed by Gene Rearrangement in NCOA2.

Autor: Jin-Wook JEONG, Michihiro KONO, Yoshie HASEGAWA-MURAKAMI, Toru MOTOI, Kenji YOKOTA, Takaaki MATSUMOTO, Kaori KAIBUCHI-ANDO, Yoichi KATO, Toyohiro TADA, Masashi AKIYAMA
Předmět:
Zdroj: Acta Dermato-Venereologica; Jan2017, Vol. 97 Issue 1, p133-134, 2p
Abstrakt: The article describes the case of a 50-year-old female patient with a history of subcutaneous mass on her left cheek and who developed angiofibroma of soft tissue (AFST) due to gene rearrangement in the nuclear receptor coactivator 2 gene (NCOA2). The diagnosis was confirmed after performing magnetic resonance imaging (MRI), histopathology, immunihistochemistry and chromogenic in situ hybridization ((CISH). A discussion on the presence of NCOA-2 in tumor cells is presented.
Databáze: Complementary Index